Many physicists, including Harry Daghlian, Jr., and Louis Slotin were killed by the atom bomb they were developing at Los Alamos.
Franz Reichelt jumped from the Eiffel Tower to test his “coat parachute” which did not function.
Fred Duesenberg was killed in a auto accident while driving a Duesenberg model.
Sylvester H. Roper designed a steam-powered bike and died of a heart attack while piloting and crashing it.
Jean-François Pilâtre de Rozier died in his own balloon invention and was the first official fatality of an air crash.
William Bullock crushed his foot while installing his rotary printing press and died of the subsequent gangrene.
Thomas Andrews, the shipbuilder in charge of drafting the plans for the Titanic, was on board the liner when it went under.
The effects of radiation killed Marie Curie while she was discovering the process of isolating radium.
Karel Soucek invented a cushioned barrel for stunt work and was killed while demonstrating it by being dropped from the top of the Astrodome.
Li Si, who came up with and implemented the “Five Pains” (a method of torture and punishment in China).